| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MAPKBP1 |
| Gene ID: | 23005 |
| Uniprot ID: | MABP1_HUMAN |
| Immunogen Region: | 1-100 |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human MAPKBP1 (NP_001122080.1). |
| Immunogen Sequence: | MAVEGSTITSRIKNLLRSPS IKLRRSKAGNRREDLSSKVT LEKVLGITVSGGRGLACDPR SGLVAYPAGCVVVLFNPRKH KQHHILNSSRKTITALAFSP |
| Tissue Specificity | Expressed in intestinal mucosa, where it is detected in epithelial cells, endothelial cells, smooth muscle cells and immune cells, such as lymphocytes. Expressed in kidney. |
| Function | Negative regulator of NOD2 function. It down-regulates NOD2-induced processes such as activation of NF-kappa-B signaling, IL8 secretion and antibacterial response. Involved in JNK signaling pathway. |
| Protein Name | Mitogen-Activated Protein Kinase-Binding Protein 1Jnk-Binding Protein 1Jnkbp-1 |
| Cellular Localisation | CytoplasmNucleusCytoskeletonSpindle PoleNot Detected In The CiliumLocalized Around The Poles Of The Mitotic Spindle From Prophase To Anaphase In Mitotic Cells |
| Alternative Antibody Names | Anti-Mitogen-Activated Protein Kinase-Binding Protein 1 antibodyAnti-Jnk-Binding Protein 1 antibodyAnti-Jnkbp-1 antibodyAnti-MAPKBP1 antibodyAnti-JNKBP1 antibodyAnti-KIAA0596 antibody |
Information sourced from Uniprot.org
