| Host: |
Rabbit |
| Applications: |
WB/IHC/IF |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit monoclonal antibody anti-JNK1/3 (1-383) is suitable for use in Western Blot, Immunohistochemistry and Immunofluorescence research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
S2MR |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000IHC-P 1:50-1:200IF/ICC 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Immunogen Region: |
1-383 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-383 of human JNK1 (P45983). |
| Immunogen Sequence: |
MSRSKRDNNFYSVEIGDSTF TVLKRYQNLKPIGSGAQGIV CAAYDAILERNVAIKKLSRP FQNQTHAKRAYRELVLMKCV NHKNIIGLLNVFTPQKSLEE FQDVYIVMELMDANLCQVIQ MELDHERMSYLLYQMLCGIK HLHSAGIIHRDLKPSNIVVK SDCTLKILDFGLARTAGTSF MMTPYVVTRYYRAPEVILGM GYKENVDLWSVGCIMGEMVC HKILFPGRDYIDQWNKVIE |
| Background | This gene encodes a protein belonging to the 14-3-3 family of proteins, members of which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals. The encoded protein has been shown to interact with RAF1 and CDC25 phosphatases, suggesting that it may play a role in linking mitogenic signaling and the cell cycle machinery. Two transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008] |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
