• Western blot with Anti-MAPK4 Antibody (STJ501705) of rat heart. Antibody is at 1:500 dilution in 1% milk.

Anti-MAPK4 antibody (500-550) (STJ501705)

SKU:
STJ501705-100

£441.50
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Host: Chicken
Applications: ELISA/IP/WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Chicken polyclonal antibody anti-MAPK4 (500-550) is suitable for use in ELISA, Immunoprecipitation and Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgY
Purification: Affinity Purified
Concentration: 0.5 µg/µl
Dilution Range: WB: 1:500
ELISA: 1:10, 000
IP: 1:150
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: MAPK4
Gene ID: 5596
Uniprot ID: MK04_HUMAN
Immunogen Region: 500-550
Immunogen: Synthetic peptide taken within amino acid region 500-550 on human Mitogen-activated protein kinase 4.
Tissue Specificity High expression in heart and brain.
Post Translational Modifications Phosphorylated at Ser-186 by PAK1, PAK2 and PAK3 resulting in catalytic activation. Phosphorylated by MAPKAPK5 at other sites.
Function Atypical MAPK protein. Phosphorylates microtubule-associated protein 2 (MAP2) and MAPKAPK5. The precise role of the complex formed with MAPKAPK5 is still unclear, but the complex follows a complex set of phosphorylation events: upon interaction with atypical MAPKAPK5, ERK4/MAPK4 is phosphorylated at Ser-186 and then mediates phosphorylation and activation of MAPKAPK5, which in turn phosphorylates ERK4/MAPK4. May promote entry in the cell cycle.
Protein Name Mitogen-Activated Protein Kinase 4
Map Kinase 4
Mapk 4
Extracellular Signal-Regulated Kinase 4
Erk-4
Map Kinase Isoform P63
P63-Mapk
Database Links Reactome: R-HSA-5687128
Cellular Localisation Cytoplasm
Nucleus
Translocates To The Cytoplasm Following Interaction With Mapkapk5
Alternative Antibody Names Anti-Mitogen-Activated Protein Kinase 4 antibody
Anti-Map Kinase 4 antibody
Anti-Mapk 4 antibody
Anti-Extracellular Signal-Regulated Kinase 4 antibody
Anti-Erk-4 antibody
Anti-Map Kinase Isoform P63 antibody
Anti-P63-Mapk antibody
Anti-MAPK4 antibody
Anti-ERK4 antibody
Anti-PRKM4 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance