| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit monoclonal antibody anti-MEKK3 (1-100) is suitable for use in Western Blot research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
S0MR |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
MAP3K3 |
| Gene ID: |
4215 |
| Uniprot ID: |
M3K3_HUMAN |
| Immunogen Region: |
1-100 |
| Immunogen: |
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human MEKK3 (Q99759). |
| Immunogen Sequence: |
MDEQEALNSIMNDLVALQMN RRHRMPGYETMKNKDTGHSN RQSDVRIKFEHNGERRIIAF SRPVKYEDVEHKVTTVFGQP LDLHYMNNELSILLKNQDDL |
| Post Translational Modifications | Phosphorylation at Ser-166 and Ser-337 by SGK1 inhibits its activity. |
| Function | Component of a protein kinase signal transduction cascade. Mediates activation of the NF-kappa-B, AP1 and DDIT3 transcriptional regulators. |
| Protein Name | Mitogen-Activated Protein Kinase Kinase Kinase 3Mapk/Erk Kinase Kinase 3Mek Kinase 3Mekk 3 |
| Database Links | Reactome: R-HSA-9020702 |
| Alternative Antibody Names | Anti-Mitogen-Activated Protein Kinase Kinase Kinase 3 antibodyAnti-Mapk/Erk Kinase Kinase 3 antibodyAnti-Mek Kinase 3 antibodyAnti-Mekk 3 antibodyAnti-MAP3K3 antibodyAnti-MAPKKK3 antibodyAnti-MEKK3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
