Host: | Mouse |
Applications: | WB/IF/ELISA |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Mouse monoclonal antibody anti-Mitogen-activated protein kinase kinase kinase 2 is suitable for use in Western Blot, Immunofluorescence and ELISA research applications. |
Clonality : | Monoclonal |
Clone ID : | 4B4 |
Conjugation: | Unconjugated |
Isotype: | IgG1 |
Formulation: | Liquid in PBS containing 0.03% Sodium Azide, 0.5% BSA, 50% Glycerol. |
Purification: | Affinity purification |
Dilution Range: | WB 1:500-1:2000IF 1:200-1:1000ELISA 1:10000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | MAP3K2 |
Gene ID: | 10746 |
Uniprot ID: | M3K2_HUMAN |
Specificity: | MEK Kinase-2 Monoclonal Antibody detects endogenous levels of MEK Kinase-2 protein. |
Immunogen: | Purified recombinant fragment of human MEK Kinase-2 expressed in E. Coli. |
Function | Component of a protein kinase signal transduction cascade. Regulates the JNK and ERK5 pathways by phosphorylating and activating MAP2K5 and MAP2K7. Plays a role in caveolae kiss-and-run dynamics. |
Protein Name | Mitogen-Activated Protein Kinase Kinase Kinase 2Mapk/Erk Kinase Kinase 2Mek Kinase 2Mekk 2 |
Cellular Localisation | CytoplasmNucleusUpon Egf StimulationTranslocates Into The Nucleus |
Alternative Antibody Names | Anti-Mitogen-Activated Protein Kinase Kinase Kinase 2 antibodyAnti-Mapk/Erk Kinase Kinase 2 antibodyAnti-Mek Kinase 2 antibodyAnti-Mekk 2 antibodyAnti-MAP3K2 antibodyAnti-MAPKKK2 antibodyAnti-MEKK2 antibody |
Information sourced from Uniprot.org