Anti-MAP3K13 antibody (151-200 aa) (STJ93975)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human M3K13 at the amino acid range 151-200
General Information
| Short Description | Rabbit polyclonal anti-Mitogen-activated protein kinase kinase kinase 13 (151-200 aa) for use in WB, IHC, IF and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IHC 1:100-1:300ELISA 1:20000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MAP3K13 |
| Gene ID | 9175 |
| Uniprot ID | M3K13_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human M3K13 at the amino acid range 151-200 |
| Immunogen Region | 151-200 aa |
| Specificity | LZK Polyclonal Antibody detects endogenous levels of LZK protein. |
Additional Info
| Post Translational Modifications | Autophosphorylated on serine and threonine residues. |
| Function | Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. Acts synergistically with PRDX3 to regulate the activation of NF-kappa-B in the cytosol. This activation is kinase-dependent and involves activating the IKK complex, the IKBKB-containing complex that phosphorylates inhibitors of NF-kappa-B. |
| Protein Name | Mitogen-Activated Protein Kinase Kinase Kinase 13Leucine Zipper-Bearing KinaseMixed Lineage KinaseMlk |
| Database Links | |
| Cellular Localisation | CytoplasmMembranePeripheral Membrane Protein |
| Alternative Antibody Names | Anti-Mitogen-Activated Protein Kinase Kinase Kinase 13 antibodyAnti-Leucine Zipper-Bearing Kinase antibodyAnti-Mixed Lineage Kinase antibodyAnti-Mlk antibodyAnti-MAP3K13 antibodyAnti-LZK antibody |
Information sourced from Uniprot.org