| Host: |
Mouse |
| Applications: |
ELISA/FC/WB/IHC |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Mouse monoclonal antibody anti-MAP3K1 is suitable for use in ELISA, Flow Cytometry, Western Blot and Immunohistochemistry research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
EBS-T-008 |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG2ak |
| Formulation: |
PBS with 0.02% Sodium Azide. |
| Purification: |
Affinity purified from tissue culture. |
| Concentration: |
Can be provided as 100 µg/mL, 500 µg/mL or 1mg/mL. |
| Dilution Range: |
ELISA (solid phase: 0, 1-100 µg/ml; tracer: 0, 001-100 µg/ml for 30 min at RT). Flow Cytometry (0, 5-1 µg/million cells in 0.1 ml). Immunoblotting (0, 5-1 µg/ml). Immunohistology (0, 5-1, 0 µg/ml for 30 minutes at RT; Staining of formalin-fixed tissu |
| Storage Instruction: |
Store for up to 1 year at 2-8°C upon receipt. |
| Gene Symbol: |
MAP3K1 |
| Gene ID: |
4214 |
| Uniprot ID: |
M3K1_HUMAN |
| Immunogen: |
A BALB/c mouse was immunized with partial recombinant MAP3K1 (aa1211-1310). Fusion partner: Sp2/0. |
| Post Translational Modifications | Autophosphorylated. |
| Function | Component of a protein kinase signal transduction cascade. Activates the ERK and JNK kinase pathways by phosphorylation of MAP2K1 and MAP2K4. May phosphorylate the MAPK8/JNK1 kinase. Activates CHUK and IKBKB, the central protein kinases of the NF-kappa-B pathway. |
| Protein Name | Mitogen-Activated Protein Kinase Kinase Kinase 1Mapk/Erk Kinase Kinase 1Mek Kinase 1Mekk 1 |
| Database Links | Reactome: R-HSA-166058Reactome: R-HSA-2871796Reactome: R-HSA-933542Reactome: R-HSA-975138Reactome: R-HSA-975871 |
| Alternative Antibody Names | Anti-Mitogen-Activated Protein Kinase Kinase Kinase 1 antibodyAnti-Mapk/Erk Kinase Kinase 1 antibodyAnti-Mek Kinase 1 antibodyAnti-Mekk 1 antibodyAnti-MAP3K1 antibodyAnti-MAPKKK1 antibodyAnti-MEKK antibodyAnti-MEKK1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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