| Short Description : | Rabbit monoclonal Monoamine Oxidase B (1-100) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IHC-P/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | S7MR |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:1000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MAOB |
| Gene ID: | 4129 |
| Uniprot ID: | AOFB_HUMAN |
| Immunogen Region: | 1-100 |
| Immunogen Sequence: | MSNKCDVVVVGGGISGMAAA KLLHDSGLNVVVLEARDRVG GRTYTLRNQKVKYVDLGGSY VGPTQNRILRLAKELGLETY KVNEVERLIHHVKGKSYPFR |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Monoamine Oxidase B (MAOB) (P27338). |
| Function | Catalyzes the oxidative deamination of primary and some secondary amines such as neurotransmitters, and exogenous amines including the tertiary amine, neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP), with concomitant reduction of oxygen to hydrogen peroxide and participates in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. Preferentially degrades benzylamine and phenylethylamine. |
| Protein Name | Amine Oxidase Flavin-Containing BMonoamine Oxidase Type BMao-B |
| Database Links | Reactome: R-HSA-141333 |
| Cellular Localisation | Mitochondrion Outer MembraneSingle-Pass Type Iv Membrane ProteinCytoplasmic Side |
| Alternative Antibody Names | Anti-Amine Oxidase Flavin-Containing B antibodyAnti-Monoamine Oxidase Type B antibodyAnti-Mao-B antibodyAnti-MAOB antibody |
Information sourced from Uniprot.org
