| Host: |
Rabbit |
| Applications: |
IF |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-MAOA (1-260) is suitable for use in Immunofluorescence research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
IF/ICC 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
MAOA |
| Gene ID: |
4128 |
| Uniprot ID: |
AOFA_HUMAN |
| Immunogen Region: |
1-260 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human Monoamine Oxidase A (Monoamine Oxidase A (MAOA) ) (NP_000231.1). |
| Immunogen Sequence: |
MENQEKASIAGHMFDVVVIG GGISGLSAAKLLTEYGVSVL VLEARDRVGGRTYTIRNEHV DYVDVGGAYVGPTQNRILRL SKELGIETYKVNVSERLVQY VKGKTYPFRGAFPPVWNPIA YLDYNNLWRTIDNMGKEIPT DAPWEAQHADKWDKMTMKEL IDKICWTKTARRFAYLFVNI NVTSEPHEVSALWFLWYVKQ CGGTTRIFSVTNGGQERKFV GGSGQVSERIMDLLGDQVK |
| Tissue Specificity | Heart, liver, duodenum, blood vessels and kidney. |
| Function | Catalyzes the oxidative deamination of primary and some secondary amine such as neurotransmitters, with concomitant reduction of oxygen to hydrogen peroxide and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. Preferentially oxidizes serotonin. Also catalyzes the oxidative deamination of kynuramine to 3-(2-aminophenyl)-3-oxopropanal that can spontaneously condense to 4-hydroxyquinoline. |
| Protein Name | Amine Oxidase Flavin-Containing AMonoamine Oxidase Type AMao-A |
| Database Links | Reactome: R-HSA-141333Reactome: R-HSA-181430Reactome: R-HSA-379397Reactome: R-HSA-379398Reactome: R-HSA-379401Reactome: R-HSA-380612Reactome: R-HSA-5579012Reactome: R-HSA-6785807 |
| Cellular Localisation | Mitochondrion Outer MembraneSingle-Pass Type Iv Membrane ProteinCytoplasmic Side |
| Alternative Antibody Names | Anti-Amine Oxidase Flavin-Containing A antibodyAnti-Monoamine Oxidase Type A antibodyAnti-Mao-A antibodyAnti-MAOA antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
![Western blot analysis of lysates from wild type (WT) and APEH knockout (KO) 293T cells, using [KO Validated] APEH Rabbit polyclonal antibody (STJ11100788) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/300x300/products/89724/358205/STJ11100788_1__51624.1713122526.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and APEH knockout (KO) 293T cells, using [KO Validated] APEH Rabbit polyclonal antibody (STJ11100788) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.")