| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-MAN1C1 (44-240) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
MAN1C1 |
| Gene ID: |
57134 |
| Uniprot ID: |
MA1C1_HUMAN |
| Immunogen Region: |
44-240 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 44-240 of human MAN1C1 (NP_065112.1). |
| Immunogen Sequence: |
PHSSRLKRLFLAPRTQQPGL EVVAEIAGHAPAREQEPPPN PAPAAPAPGEDDPSSWASPR RRKGGLRRTRPTGPREEATA ARGNSIPASRPGDEGVPFRF DFNAFRSRLRHPVLGTRADE SQEPQSQVRAQREKIKEMMQ FAWQSYKRYAMGKNELRPLT KDGYEGNMFGGLSGATVIDS LDTLYLMELKEEFQEAK |
| Tissue Specificity | Expressed in most tissues with the exception of lung, muscle and pancreas. Highly expressed in placenta. |
| Function | Involved in the maturation of Asn-linked oligosaccharides. Trim alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce first Man(8)GlcNAc(2) then Man(6)GlcNAc and a small amount of Man(5)GlcNAc. |
| Protein Name | Mannosyl-Oligosaccharide 1 -2-Alpha-Mannosidase IcHmicMannosidase Alpha Class 1c Member 1Processing Alpha-1 -2-Mannosidase IcAlpha-1 -2-Mannosidase Ic |
| Database Links | Reactome: R-HSA-6811438Reactome: R-HSA-964827 |
| Cellular Localisation | Golgi Apparatus MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-Mannosyl-Oligosaccharide 1 -2-Alpha-Mannosidase Ic antibodyAnti-Hmic antibodyAnti-Mannosidase Alpha Class 1c Member 1 antibodyAnti-Processing Alpha-1 -2-Mannosidase Ic antibodyAnti-Alpha-1 -2-Mannosidase Ic antibodyAnti-MAN1C1 antibodyAnti-MAN1A3 antibodyAnti-MAN1C antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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