Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using MAGE-1 Antibody. The picture on the right is blocked with the synthesized peptide.

Anti-MAGEA1 antibody (260-309 aa) (STJ93988)

SKU:
STJ93988
£48.00 - £252.00
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Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-Melanoma-associated antigen 1 (260-309 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:10000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: MAGEA1
Gene ID: 4100
Uniprot ID: MAGA1_HUMAN
Immunogen Region: 260-309 aa
Specificity: MAGE-1 Polyclonal Antibody detects endogenous levels of MAGE-1 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human MAGE-1 at the amino acid range 260-309
Function May be involved in transcriptional regulation through interaction with SNW1 and recruiting histone deactelyase HDAC1. May inhibit notch intracellular domain (NICD) transactivation. May play a role in embryonal development and tumor transformation or aspects of tumor progression. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes.
Protein Name Melanoma-Associated Antigen 1
Antigen Mz2-E
Cancer/Testis Antigen 1.1
Ct1.1
Mage-1 Antigen
Cellular Localisation Cytoplasm
Nucleus
Alternative Antibody Names Anti-Melanoma-Associated Antigen 1 antibody
Anti-Antigen Mz2-E antibody
Anti-Cancer/Testis Antigen 1.1 antibody
Anti-Ct1.1 antibody
Anti-Mage-1 Antigen antibody
Anti-MAGEA1 antibody
Anti-MAGE1 antibody
Anti-MAGE1A antibody

Information sourced from Uniprot.org

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