| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Transcription factor MafA (204-254 aa) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
MAFA |
| Gene ID: |
389692 |
| Uniprot ID: |
MAFA_HUMAN |
| Immunogen Region: |
204-254 aa |
| Specificity: |
This antibody detects endogenous levels of MAFA at Human/Mouse |
| Immunogen: |
Synthesized peptide derived from the human MAFA at the amino acid range 204-254 |
| Post Translational Modifications | Ubiquitinated, leading to its degradation by the proteasome. Phosphorylated at tyrosines. |
| Function | Transcription factor that activates insulin gene expression. Acts synergistically with NEUROD1/BETA2 and PDX1. Binds the insulin enhancer C1/RIPE3b element. Binds to consensus TRE-type MARE 5'-TGCTGACTCAGCA-3' DNA sequence. |
| Protein Name | Transcription Factor MafaPancreatic Beta-Cell-Specific Transcriptional ActivatorRipe3b1 FactorV-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog A |
| Database Links | Reactome: R-HSA-210745 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Transcription Factor Mafa antibodyAnti-Pancreatic Beta-Cell-Specific Transcriptional Activator antibodyAnti-Ripe3b1 Factor antibodyAnti-V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog A antibodyAnti-MAFA antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
