• Western blot analysis of lysates from MDA-MB cells, primary antibody was diluted at 1:1000, 4°C over night

Anti-MAFA antibody (204-254 aa) (STJ193496)

SKU:
STJ193496

Current Stock:
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Transcription factor MafA (204-254 aa) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: MAFA
Gene ID: 389692
Uniprot ID: MAFA_HUMAN
Immunogen Region: 204-254 aa
Specificity: This antibody detects endogenous levels of MAFA at Human/Mouse
Immunogen: Synthesized peptide derived from the human MAFA at the amino acid range 204-254
Post Translational Modifications Ubiquitinated, leading to its degradation by the proteasome. Phosphorylated at tyrosines.
Function Transcription factor that activates insulin gene expression. Acts synergistically with NEUROD1/BETA2 and PDX1. Binds the insulin enhancer C1/RIPE3b element. Binds to consensus TRE-type MARE 5'-TGCTGACTCAGCA-3' DNA sequence.
Protein Name Transcription Factor Mafa
Pancreatic Beta-Cell-Specific Transcriptional Activator
Ripe3b1 Factor
V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog A
Database Links Reactome: R-HSA-210745
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Transcription Factor Mafa antibody
Anti-Pancreatic Beta-Cell-Specific Transcriptional Activator antibody
Anti-Ripe3b1 Factor antibody
Anti-V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog A antibody
Anti-MAFA antibody

Information sourced from Uniprot.org

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