| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | S8MR |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MXD3 |
| Gene ID: | 83463 |
| Uniprot ID: | MAD3_HUMAN |
| Immunogen Region: | 100-190 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 100-190 of human MAD3/MXD3 (Q9BW11). |
| Immunogen Sequence: | RRARMHIQKLEDQEQRARQL KERLRSKQQSLQRQLEQLRG LAGAAERERLRADSLDSSGL SSERSDSDQEELEVDVESLV FGGEAELLRGF |
| Function | Transcriptional repressor. Binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CACGATG-3'. Antagonizes MYC transcriptional activity by competing for MAX and suppresses MYC dependent cell transformation. |
| Protein Name | Max Dimerization Protein 3Max Dimerizer 3Class C Basic Helix-Loop-Helix Protein 13Bhlhc13Max-Associated Protein 3Max-Interacting Transcriptional Repressor Mad3Myx |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Max Dimerization Protein 3 antibodyAnti-Max Dimerizer 3 antibodyAnti-Class C Basic Helix-Loop-Helix Protein 13 antibodyAnti-Bhlhc13 antibodyAnti-Max-Associated Protein 3 antibodyAnti-Max-Interacting Transcriptional Repressor Mad3 antibodyAnti-Myx antibodyAnti-MXD3 antibodyAnti-BHLHC13 antibodyAnti-MAD3 antibody |
Information sourced from Uniprot.org