| Short Description : | Rabbit polyclonal anti-MACC1 (500-550 aa) for use in IHC and WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | IHC/WB |
| Host: | Rabbit |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Purification: | IgG purified |
| Dilution Range: | IHC, WB (confirmed by recombinant protein). A dilution of 1:300 to 1:2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Formulation: | Lyophilised |
| Storage Instruction: | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
| Gene Symbol: | MACC1 |
| Gene ID: | 346389 |
| Uniprot ID: | MACC1_HUMAN |
| Immunogen: | A synthetic peptide from aa region 500-550 of human MACC1 conjugated to an immunogenic carrier protein was used as the antigen. |
| Immunogen Region: | 500-550 aa |
| Specificity: | Specific for MACC1. |
| Function | Acts as a transcription activator for MET and as a key regulator of HGF-MET signaling. Promotes cell motility, proliferation and hepatocyte growth factor (HGF)-dependent scattering in vitro and tumor growth and metastasis in vivo. |
| Protein Name | Metastasis-Associated In Colon Cancer Protein 1Sh3 Domain-Containing Protein 7a5 |
| Database Links | |
| Cellular Localisation | CytoplasmNucleusMainly Found In The Cytoplasm In Non-Metastasizing Tumors |
| Alternative Antibody Names | Anti-Metastasis-Associated In Colon Cancer Protein 1 antibodyAnti-Sh3 Domain-Containing Protein 7a5 antibodyAnti-MACC1 antibody |
Information sourced from Uniprot.org
