Anti-LZTS2 antibody (STJA0007394)

SKU:
STJA0007394

Current Stock:
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Leucine zipper putative tumor suppressor 2 is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: LZTS2
Gene ID: 84445
Uniprot ID: LZTS2_HUMAN
Specificity: This antibody detects endogenous levels of LZTS2 at Human, Mouse, Rat
Immunogen: Synthesized peptide derived from human LZTS2
Function Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. May negatively regulate axonal outgrowth by preventing the formation of microtubule bundles that are necessary for transport within the elongating axon. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta-catenin.
Protein Name Leucine Zipper Putative Tumor Suppressor 2
Hlzts2
Protein Lapser1
Cellular Localisation Cytoplasm
Cytoskeleton
Microtubule Organizing Center
Centrosome
Localized To The Centrosome Throughout The Cell Cycle
Localized To The Midbody In Cells Undergoing Cytokinesis
Alternative Antibody Names Anti-Leucine Zipper Putative Tumor Suppressor 2 antibody
Anti-Hlzts2 antibody
Anti-Protein Lapser1 antibody
Anti-LZTS2 antibody
Anti-KIAA1813 antibody
Anti-LAPSER1 antibody

Information sourced from Uniprot.org

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