| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Leucine-zipper-like transcriptional regulator 1 (310-390 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000ELISA 1:5000-20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | LZTR1 |
| Gene ID: | 8216 |
| Uniprot ID: | LZTR1_HUMAN |
| Immunogen Region: | 310-390 aa |
| Specificity: | LZTR1 Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: | Synthesized peptide derived from the human protein at the amino acid range 310-390 |
| Function | Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates ubiquitination of Ras (K-Ras/KRAS, N-Ras/NRAS and H-Ras/HRAS). Is a negative regulator of RAS-MAPK signaling that acts by controlling Ras levels and decreasing Ras association with membranes. |
| Protein Name | Leucine-Zipper-Like Transcriptional Regulator 1Lztr-1 |
| Cellular Localisation | Endomembrane SystemRecycling EndosomeGolgi Apparatus |
| Alternative Antibody Names | Anti-Leucine-Zipper-Like Transcriptional Regulator 1 antibodyAnti-Lztr-1 antibodyAnti-LZTR1 antibodyAnti-TCFL2 antibody |
Information sourced from Uniprot.org