Anti-LYPLA2 antibody (30-110 aa) (STJ190508)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human protein at the amino acid range 30-110
General Information
| Short Description | Rabbit polyclonal anti-Acyl-protein thioesterase 2 (30-110 aa) for use in WB and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | LYPLA2 |
| Gene ID | 11313 |
| Uniprot ID | LYPA2_HUMAN |
| Immunogen | Synthesized peptide derived from the human protein at the amino acid range 30-110 |
| Immunogen Region | 30-110 aa |
| Specificity | LYPA2 Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Function | Acts as an acyl-protein thioesterase hydrolyzing fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins, GSDMD, GAP43, ZDHHC6 or HRAS. Deacylates GAP43. Mediates depalmitoylation of ZDHHC6. Has lysophospholipase activity. Hydrolyzes prostaglandin glycerol esters (PG-Gs) in the following order prostaglandin D2-glycerol ester (PGD2-G) > prostaglandin E2 glycerol ester (PGE2-G) > prostaglandin F2-alpha-glycerol ester (PGF2-alpha-G). Hydrolyzes 1-arachidonoylglycerol but not 2-arachidonoylglycerol or arachidonoylethanolamide. |
| Protein Name | Acyl-Protein Thioesterase 2Apt-2Lysophospholipase IiLpl-IiLysopla IiPalmitoyl-Protein Hydrolase |
| Database Links | Reactome: R-HSA-373760 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Acyl-Protein Thioesterase 2 antibodyAnti-Apt-2 antibodyAnti-Lysophospholipase Ii antibodyAnti-Lpl-Ii antibodyAnti-Lysopla Ii antibodyAnti-Palmitoyl-Protein Hydrolase antibodyAnti-LYPLA2 antibodyAnti-APT2 antibody |
Information sourced from Uniprot.org