| Short Description : | Mouse monoclonal Lymphocyte antigen 6h antibody for use in ELISA and FC in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | ELISA/FC |
| Host: | Mouse |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | 12G7 |
| Isotype: | IgG2ak |
| Conjugation: | PerCP |
| Concentration: | 0.5 mg/mL |
| Purification: | Purified |
| Formulation: | PBS pH 7.4, 50% glycerol, 0.05% proclin300 |
| Storage Instruction: | Store at 4°C for 12 months. Protect from light. Do not freeze. |
| Gene Symbol: | LY6H |
| Gene ID: | 4062 |
| Uniprot ID: | LY6H_HUMAN |
| Function | Believed to act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro inhibits alpha-3:beta-4-containing nAChRs maximum response. May play a role in the intracellular trafficking of alpha-7-containing nAChRs and may inhibit their expression at the cell surface. Seems to inhibit alpha-7/CHRNA7 signaling in hippocampal neurons. |
| Protein Name | Lymphocyte Antigen 6hLy-6h |
| Database Links | Reactome: R-HSA-163125 |
| Cellular Localisation | Cell MembraneLipid-AnchorGpi-Anchor |
| Alternative Antibody Names | Anti-Lymphocyte Antigen 6h antibodyAnti-Ly-6h antibodyAnti-LY6H antibody |
Information sourced from Uniprot.org