Anti-LTBR antibody (101-200 aa) [SRM5282] (STJ11107184)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal LTBR (101-200 aa) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SRM5282 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS withΒ 0.09% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3. |
| Storage Instruction | Store at-20Β°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | LTBR |
| Gene ID | 4055 |
| Uniprot ID | TNR3_HUMAN |
| Immunogen Region | 101-200 aa |
| Immunogen Sequence | CRPCDPVMGLEEIAPCTSKR KTQCRCQPGMFCAAWALECT HCELLSDCPPGTEAELKDEV GKGNNHCVPCKAGHFQNTSS PSARCQPHTRCENQGLVEAA |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 101-200 of human LTBR (NP_002333.1). |
Additional Info
| Function | Receptor for the heterotrimeric lymphotoxin containing LTA and LTB, and for TNFS14/LIGHT. Activates NF-kappa-B signaling pathway upon stimulation with lymphotoxin (LTA(1)-LTB(2)). Promotes apoptosis via TRAF3 and TRAF5. May play a role in the development of lymphoid organs. |
| Protein Name | Tumor Necrosis Factor Receptor Superfamily Member 3Lymphotoxin-Beta ReceptorTumor Necrosis Factor C ReceptorTumor Necrosis Factor Receptor 2-Related ProteinTumor Necrosis Factor Receptor Type IiiTnf-RiiiTnfr-Iii |
| Database Links | Reactome: R-HSA-5668541Reactome: R-HSA-5676594 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Tumor Necrosis Factor Receptor Superfamily Member 3 antibodyAnti-Lymphotoxin-Beta Receptor antibodyAnti-Tumor Necrosis Factor C Receptor antibodyAnti-Tumor Necrosis Factor Receptor 2-Related Protein antibodyAnti-Tumor Necrosis Factor Receptor Type Iii antibodyAnti-Tnf-Riii antibodyAnti-Tnfr-Iii antibodyAnti-LTBR antibodyAnti-D12S370 antibodyAnti-TNFCR antibodyAnti-TNFR3 antibodyAnti-TNFRSF3 antibody |
Information sourced from Uniprot.org