| Short Description : | Rabbit monoclonal LTBR (101-200 aa) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | SRM5282 |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.09% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | LTBR |
| Gene ID: | 4055 |
| Uniprot ID: | TNR3_HUMAN |
| Immunogen Region: | 101-200 aa |
| Immunogen Sequence: | CRPCDPVMGLEEIAPCTSKR KTQCRCQPGMFCAAWALECT HCELLSDCPPGTEAELKDEV GKGNNHCVPCKAGHFQNTSS PSARCQPHTRCENQGLVEAA |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 101-200 of human LTBR (NP_002333.1). |
| Function | Receptor for the heterotrimeric lymphotoxin containing LTA and LTB, and for TNFS14/LIGHT. Activates NF-kappa-B signaling pathway upon stimulation with lymphotoxin (LTA(1)-LTB(2)). Promotes apoptosis via TRAF3 and TRAF5. May play a role in the development of lymphoid organs. |
| Protein Name | Tumor Necrosis Factor Receptor Superfamily Member 3Lymphotoxin-Beta ReceptorTumor Necrosis Factor C ReceptorTumor Necrosis Factor Receptor 2-Related ProteinTumor Necrosis Factor Receptor Type IiiTnf-RiiiTnfr-Iii |
| Database Links | Reactome: R-HSA-5668541Reactome: R-HSA-5676594 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Tumor Necrosis Factor Receptor Superfamily Member 3 antibodyAnti-Lymphotoxin-Beta Receptor antibodyAnti-Tumor Necrosis Factor C Receptor antibodyAnti-Tumor Necrosis Factor Receptor 2-Related Protein antibodyAnti-Tumor Necrosis Factor Receptor Type Iii antibodyAnti-Tnf-Riii antibodyAnti-Tnfr-Iii antibodyAnti-LTBR antibodyAnti-D12S370 antibodyAnti-TNFCR antibodyAnti-TNFR3 antibodyAnti-TNFRSF3 antibody |
Information sourced from Uniprot.org
