| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Monoclonal |
| Clone ID: |
SRM |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: |
LTBR |
| Gene ID: |
4055 |
| Uniprot ID: |
TNR3_HUMAN |
| Immunogen Region: |
101-200 aa |
| Specificity: |
A synthetic peptide corresponding to a sequence within amino acids 101-200 of human LTBR (NP_002333.1). |
| Immunogen Sequence: |
CRPCDPVMGLEEIAPCTSKR KTQCRCQPGMFCAAWALECT HCELLSDCPPGTEAELKDEV GKGNNHCVPCKAGHFQNTSS PSARCQPHTRCENQGLVEAA |
| Function | Receptor for the heterotrimeric lymphotoxin containing LTA and LTB, and for TNFS14/LIGHT. Activates NF-kappa-B signaling pathway upon stimulation with lymphotoxin (LTA(1)-LTB(2)). Promotes apoptosis via TRAF3 and TRAF5. May play a role in the development of lymphoid organs. |
| Protein Name | Tumor Necrosis Factor Receptor Superfamily Member 3Lymphotoxin-Beta ReceptorTumor Necrosis Factor C ReceptorTumor Necrosis Factor Receptor 2-Related ProteinTumor Necrosis Factor Receptor Type IiiTnf-RiiiTnfr-Iii |
| Database Links | Reactome: R-HSA-5668541Reactome: R-HSA-5676594 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Tumor Necrosis Factor Receptor Superfamily Member 3 antibodyAnti-Lymphotoxin-Beta Receptor antibodyAnti-Tumor Necrosis Factor C Receptor antibodyAnti-Tumor Necrosis Factor Receptor 2-Related Protein antibodyAnti-Tumor Necrosis Factor Receptor Type Iii antibodyAnti-Tnf-Riii antibodyAnti-Tnfr-Iii antibodyAnti-LTBR antibodyAnti-D12S370 antibodyAnti-TNFCR antibodyAnti-TNFR3 antibodyAnti-TNFRSF3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
