| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: | LTB |
| Gene ID: | 4050 |
| Uniprot ID: | TNFC_HUMAN |
| Immunogen Region: | 1-100 aa |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human LTB (NP_002332.1). |
| Immunogen Sequence: | MGALGLEGRGGRLQGRGSLL LAVAGATSLVTLLLAVPITV LAVLALVPQDQGGLVTETAD PGAQAQQGLGFQKLPEEEPE TDLSPGLPAAHLIGAPLKGQ |
| Tissue Specificity | Spleen and thymus. |
| Function | Cytokine that binds to LTBR/TNFRSF3. May play a specific role in immune response regulation. Provides the membrane anchor for the attachment of the heterotrimeric complex to the cell surface. Isoform 2 is probably non-functional. |
| Protein Name | Lymphotoxin-BetaLt-BetaTumor Necrosis Factor CTnf-CTumor Necrosis Factor Ligand Superfamily Member 3 |
| Database Links | Reactome: R-HSA-5668541Reactome: R-HSA-5676594 |
| Cellular Localisation | MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-Lymphotoxin-Beta antibodyAnti-Lt-Beta antibodyAnti-Tumor Necrosis Factor C antibodyAnti-Tnf-C antibodyAnti-Tumor Necrosis Factor Ligand Superfamily Member 3 antibodyAnti-LTB antibodyAnti-TNFC antibodyAnti-TNFSF3 antibody |
Information sourced from Uniprot.org