• Immunohistochemistry analysis of paraffin-embedded human tonsil using LTA Rabbit polyclonal antibody (STJ11103847) at dilution of 1:50 (40x lens). Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6. 0 before commencing with immunohistochemistry staining protocol.
  • Immunohistochemistry analysis of paraffin-embedded human breast cancer using LTA Rabbit polyclonal antibody (STJ11103847) at dilution of 1:50 (40x lens). Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6. 0 before commencing with immunohistochemistry staining protocol.
  • Western blot analysis of extracts of Mouse spleen, using LTA antibody (STJ11103847) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.

Anti-LTA antibody (35-205) (STJ11103847)

SKU:
STJ11103847

£112.50 - £522.50
Current Stock:
Host: Rabbit
Applications: WB/IHC
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Lymphotoxin-Alpha (35-205) is suitable for use in Western Blot and Immunohistochemistry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.05% Proclin300, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:1000
IHC-P 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: LTA
Gene ID: 4049
Uniprot ID: TNFB_HUMAN
Immunogen Region: 35-205
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 35-205 of human LTA (NP_000586.2).
Immunogen Sequence: LPGVGLTPSAAQTARQHPKM HLAHSTLKPAAHLIGDPSKQ NSLLWRANTDRAFLQDGFSL SNNSLLVPTSGIYFVYSQVV FSGKAYSPKATSSPLYLAHE VQLFSSQYPFHVPLLSSQKM VYPGLQEPWLHSMYHGAAFQ LTQGDQLSTHTDGIPHLVLS PSTVFFGAFAL
Function Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM. In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and is cytotoxic for a wide range of tumor cells in vitro and in vivo.
Protein Name Lymphotoxin-Alpha
Lt-Alpha
Tnf-Beta
Tumor Necrosis Factor Ligand Superfamily Member 1
Database Links Reactome: R-HSA-5668541
Reactome: R-HSA-5669034
Reactome: R-HSA-5676594
Cellular Localisation Secreted
Membrane
The Homotrimer Is Secreted
The Heterotrimer Is Membrane-Associated
Alternative Antibody Names Anti-Lymphotoxin-Alpha antibody
Anti-Lt-Alpha antibody
Anti-Tnf-Beta antibody
Anti-Tumor Necrosis Factor Ligand Superfamily Member 1 antibody
Anti-LTA antibody
Anti-TNFB antibody
Anti-TNFSF1 antibody

Information sourced from Uniprot.org

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