| Host: |
Rabbit |
| Applications: |
WB/IP |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-LSM4 (1-139) is suitable for use in Western Blot and Immunoprecipitation research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000IP 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
LSM4 |
| Gene ID: |
25804 |
| Uniprot ID: |
LSM4_HUMAN |
| Immunogen Region: |
1-139 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-139 of human LSM4 (NP_036453.1). |
| Immunogen Sequence: |
MLPLSLLKTAQNHPMLVELK NGETYNGHLVSCDNWMNINL REVICTSRDGDKFWRMPECY IRGSTIKYLRIPDEIIDMVK EEVVAKGRGRGGLQQQKQQK GRGMGGAGRGVFGGRGRGGI PGTGRGQPEKKPGRQAGKQ |
| Function | Plays a role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. |
| Protein Name | U6 Snrna-Associated Sm-Like Protein Lsm4Glycine-Rich ProteinGrp |
| Database Links | Reactome: R-HSA-430039Reactome: R-HSA-72163 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-U6 Snrna-Associated Sm-Like Protein Lsm4 antibodyAnti-Glycine-Rich Protein antibodyAnti-Grp antibodyAnti-LSM4 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
