| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | LSM1 |
| Gene ID: | 27257 |
| Uniprot ID: | LSM1_HUMAN |
| Immunogen Region: | 1-133 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-133 of human LSM1 (NP_055277.1). |
| Immunogen Sequence: | MNYMPGTASLIEDIDKKHLV LLRDGRTLIGFLRSIDQFAN LVLHQTVERIHVGKKYGDIP RGIFVVRGENVVLLGEIDLE KESDTPLQQVSIEEILEEQR VEQQTKLEAEKLKVQALKDR GLSIPRADTLDEY |
| Function | Plays a role in the degradation of histone mRNAs, the only eukaryotic mRNAs that are not polyadenylated. Probably also part of an LSm subunits-containing complex involved in the general process of mRNA degradation. |
| Protein Name | U6 Snrna-Associated Sm-Like Protein Lsm1Cancer-Associated Sm-LikeSmall Nuclear Ribonuclear Casm |
| Database Links | Reactome: R-HSA-430039 |
| Cellular Localisation | CytoplasmP-Body |
| Alternative Antibody Names | Anti-U6 Snrna-Associated Sm-Like Protein Lsm1 antibodyAnti-Cancer-Associated Sm-Like antibodyAnti-Small Nuclear Ribonuclear Casm antibodyAnti-LSM1 antibodyAnti-CASM antibody |
Information sourced from Uniprot.org
![Immunofluorescence analysis of U-2 OS cells using [KO Validated] IFITM3 Rabbit polyclonal antibody (STJ115037) at dilution of 1:100. Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) at 1:500 dilution. Blue: DAPI for nuclear staining.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/600x533/products/94077/375456/STJ115037_1__41009.1713142223.jpg?c=1 "Immunofluorescence analysis of U-2 OS cells using [KO Validated] IFITM3 Rabbit polyclonal antibody (STJ115037) at dilution of 1:100. Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) at 1:500 dilution. Blue: DAPI for nuclear staining.")
