• Western blot detection of LRRFIP1 in Raji, C2C12, MCF7 and Jurkat cell lysates using LRRFIP1 mouse mAb (1:1000 diluted).Predicted band size:89KDa.Observed band size:160KDa.

Anti-LRRFIP1 antibody [4F3-D8-C9] (STJ99142)

SKU:
STJ99142

£139.00 - £336.00
Current Stock:
Host: Mouse
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-Leucine-rich repeat flightless-interacting protein 1 is suitable for use in Western Blot research applications.
Clonality: Monoclonal
Clone ID: 4F3-D8-C9
Conjugation: Unconjugated
Isotype: IgG1
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:1000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: LRRFIP1
Gene ID: 9208
Uniprot ID: LRRF1_HUMAN
Specificity: This antibody detects endogenous levels of LRRFIP1 and does not cross-react with related proteins.
Immunogen: Purified recombinant human LRRFIP1 protein fragments expressed in E.coli.
Function Transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'-AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA. May control smooth muscle cells proliferation following artery injury through PDGFA repression. May also bind double-stranded RNA. Positively regulates Toll-like receptor (TLR) signaling in response to agonist probably by competing with the negative FLII regulator for MYD88-binding.
Protein Name Leucine-Rich Repeat Flightless-Interacting Protein 1
Lrr Flii-Interacting Protein 1
Gc-Binding Factor 2
Tar Rna-Interacting Protein
Database Links Reactome: R-HSA-1839117
Reactome: R-HSA-3134973
Reactome: R-HSA-5655302
Cellular Localisation Nucleus
Cytoplasm
Alternative Antibody Names Anti-Leucine-Rich Repeat Flightless-Interacting Protein 1 antibody
Anti-Lrr Flii-Interacting Protein 1 antibody
Anti-Gc-Binding Factor 2 antibody
Anti-Tar Rna-Interacting Protein antibody
Anti-LRRFIP1 antibody
Anti-GCF2 antibody
Anti-TRIP antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance