Host: |
Rabbit |
Applications: |
WB/IHC/ELISA |
Reactivity: |
Human/Mouse |
Note: |
FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Leucine-Rich Repeat-Containing Protein 19 is suitable for use in Western Blot, Immunohistochemistry and ELISA research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4 |
Purification: |
Antigen affinity purification |
Concentration: |
1.1 mg/mL |
Dilution Range: |
WB 1:500-1:2000, IHC 1:25-1:100 |
Storage Instruction: |
Store at-20°C for long term, and avoid freeze-thaw cycles. |
Tissue Specificity | Expressed in renal collecting duct epithelial cells. |
Function | Pathogen-recognition receptor which mediates the activation of TRAF2- and TRAF6 NF-kappa-B signaling pathways and induces the expression of pro-inflammatory cytokines. In kidney, prevents infection by uropathogenic bacteria by inducing the production of cytokines, chemokines and antimicrobial substances. In gut, involved in host-microbiota interactions, plays a critical role in promoting the recruitment of immune cells and intestinal inflammation. |
Protein Name | Leucine-Rich Repeat-Containing Protein 19 |
Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
Alternative Antibody Names | Anti-Leucine-Rich Repeat-Containing Protein 19 antibodyAnti-LRRC19 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance