| Host: | Rabbit |
| Applications: | WB/IHC/ELISA |
| Reactivity: | Human/Mouse |
| Note: | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
| Short Description : | Rabbit polyclonal anti-Leucine-Rich Repeat-Containing Protein 19 for use in WB, IHC and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% NaN3 and 40% Glycerol, pH7.4 |
| Purification: | Antigen affinity purification |
| Concentration: | 1.1 mg/mL |
| Dilution Range: | WB 1:500-1:2000, IHC 1:25-1:100 |
| Storage Instruction: | Store at-20°C for the long term, and avoid freeze-thaw cycles. |
| Gene Symbol: | LRRC19 |
| Gene ID: | 64922 |
| Uniprot ID: | LRC19_HUMAN |
| Immunogen: | Fusion protein of human LRRC19 |
| Tissue Specificity | Expressed in renal collecting duct epithelial cells. |
| Function | Pathogen-recognition receptor which mediates the activation of TRAF2- and TRAF6 NF-kappa-B signaling pathways and induces the expression of pro-inflammatory cytokines. In kidney, prevents infection by uropathogenic bacteria by inducing the production of cytokines, chemokines and antimicrobial substances. In gut, involved in host-microbiota interactions, plays a critical role in promoting the recruitment of immune cells and intestinal inflammation. |
| Protein Name | Leucine-Rich Repeat-Containing Protein 19 |
| Database Links | |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Leucine-Rich Repeat-Containing Protein 19 antibodyAnti-LRRC19 antibody |
Information sourced from Uniprot.org
