| Host: | Rabbit |
| Applications: | IHC/WB |
| Reactivity: | Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-LRFN1 (Cytoplasmic Domain) is suitable for use in Immunohistochemistry and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Lyophilised |
| Purification: | IgG purified |
| Dilution Range: | IHC, WB (confirmed by recombinant protein). A dilution of 1:300 to 1:2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Storage Instruction: | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
| Gene Symbol: | Lrfn1 |
| Gene ID: | 80749 |
| Uniprot ID: | LRFN1_MOUSE |
| Immunogen Region: | Cytoplasmic Domain |
| Specificity: | Specific for LRFN1. |
| Immunogen: | A synthetic peptide from cytoplasmic domain of mouse LRFN1 (Synaptic differentiation enhancing molecule 1) conjugated to an immunogenic carrier protein was used as the antigen. |
| Post Translational Modifications | Glycosylated. |
| Function | Promotes neurite outgrowth in hippocampal neurons. Involved in the regulation and maintenance of excitatory synapses. Induces the clustering of excitatory postsynaptic proteins, including DLG4, DLGAP1, GRIA1 and GRIN1. |
| Protein Name | Leucine-Rich Repeat And Fibronectin Type Iii Domain-Containing Protein 1Synaptic Adhesion-Like Molecule 2Synaptic Differentiation-Enhancing Molecule 1 |
| Database Links | Reactome: R-MMU-8849932 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane ProteinSynapsePostsynaptic Density MembraneDetected In ExcitatoryBut Not InhibitorySynaptic Plasma Membrane |
| Alternative Antibody Names | Anti-Leucine-Rich Repeat And Fibronectin Type Iii Domain-Containing Protein 1 antibodyAnti-Synaptic Adhesion-Like Molecule 2 antibodyAnti-Synaptic Differentiation-Enhancing Molecule 1 antibodyAnti-Lrfn1 antibodyAnti-Salm2 antibodyAnti-Semo1 antibody |
Information sourced from Uniprot.org