| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human/Rat/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Acyl-CoA:lysophosphatidylglycerol acyltransferase 1 (180-260 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000ELISA 1:5000-20000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
LPGAT1 |
| Gene ID: |
9926 |
| Uniprot ID: |
LGAT1_HUMAN |
| Immunogen Region: |
180-260 aa |
| Specificity: |
LGAT1 Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: |
Synthesized peptide derived from the human protein at the amino acid range 180-260 |
| Function | Lysophospholipid acyltransferase involved in fatty acyl chain remodeling of glycerophospholipids in the endoplasmic reticulum membrane. Selectively catalyzes the transfer and esterification of saturated long-chain fatty acids from acyl-CoA to the sn-1 position of 1-lyso-2-acyl phosphatidylethanolamines (1-lyso-PE, LPE), with a preference for stearoyl CoA over palmitoyl CoA as acyl donor. Acts in concert with an unknown phospholipase A1 to convert palmitate phosphatidylethanolamine (PE) species into stearate ones. Provides substrates to the PE methylation pathway, controlling stearate/palmitate composition of PE and phosphatidylcholine (PC) species with an overall impact on de novo hepatic lipid synthesis, body fat content and life span. Can acylate lysophosphatidylglycerols (LPG) using various saturated fatty acyl-CoAs as acyl donors. Can also acylate monoacylglycerols with a preference for 2-monoacylglycerols over 1-monoacylglycerols. Has no activity toward lysophosphatidic acids (LPA). |
| Protein Name | Acyl-Coa -Lysophosphatidylglycerol Acyltransferase 12-Acylglycerophosphocholine O-AcyltransferaseAcyl-Coa -Monoacylglycerol Acyltransferase Lpgat1Lysophospholipid Acyltransferase 7Lplat7Stearoyl-Coa -1-Lyso-2-Acyl-Pe Acyltransferase |
| Database Links | Reactome: R-HSA-1482925 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Acyl-Coa -Lysophosphatidylglycerol Acyltransferase 1 antibodyAnti-2-Acylglycerophosphocholine O-Acyltransferase antibodyAnti-Acyl-Coa -Monoacylglycerol Acyltransferase Lpgat1 antibodyAnti-Lysophospholipid Acyltransferase 7 antibodyAnti-Lplat7 antibodyAnti-Stearoyl-Coa -1-Lyso-2-Acyl-Pe Acyltransferase antibodyAnti-LPGAT1 antibodyAnti-FAM34A antibodyAnti-KIAA0205 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
