Anti-LPAR4 antibody (311-370) (STJ11103188)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal LPAR4 (311-370) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | LPAR4 |
| Gene ID | 2846 |
| Uniprot ID | LPAR4_HUMAN |
| Immunogen Region | 311-370 |
| Immunogen Sequence | YYFTLESFQKSFYINAHIRM ESLFKTETPLTTKPSLPAIQ EEVSDQTTNNGGELMLESTF |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 311-370 of human LPAR4 (Q99677). |
Additional Info
| Tissue Specificity | High expression in ovary. Not detected in the brain regions thalamus, putamen, caudate, frontal cortex, pons, hypothalamus and hippocampus. |
| Function | Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. Transduces a signal by increasing the intracellular calcium ions and by stimulating adenylyl cyclase activity. The rank order of potency for agonists of this receptor is 1-oleoyl- > 1-stearoyl- > 1-palmitoyl- > 1-myristoyl- > 1-alkyl- > 1-alkenyl-LPA. |
| Protein Name | Lysophosphatidic Acid Receptor 4Lpa Receptor 4Lpa-4G-Protein Coupled Receptor 23P2y Purinoceptor 9P2y9P2y5-Like ReceptorPurinergic Receptor 9 |
| Database Links | Reactome: R-HSA-416476Reactome: R-HSA-417957 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Lysophosphatidic Acid Receptor 4 antibodyAnti-Lpa Receptor 4 antibodyAnti-Lpa-4 antibodyAnti-G-Protein Coupled Receptor 23 antibodyAnti-P2y Purinoceptor 9 antibodyAnti-P2y9 antibodyAnti-P2y5-Like Receptor antibodyAnti-Purinergic Receptor 9 antibodyAnti-LPAR4 antibodyAnti-GPR23 antibodyAnti-LPA4 antibodyAnti-P2RY9 antibody |
Information sourced from Uniprot.org