| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Leiomodin-3 is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | LMOD3 |
| Gene ID: | 56203 |
| Uniprot ID: | LMOD3_HUMAN |
| Specificity: | This antibody detects endogenous levels of LMOD3 at Human |
| Immunogen: | Synthesized peptide derived from human LMOD3 |
| Post Translational Modifications | Ubiquitinated, leading to its degradation. Interaction with KLHL40 negatively regulates ubiquitination and degradation. |
| Function | Essential for the organization of sarcomeric actin thin filaments in skeletal muscle. Increases the rate of actin polymerization. |
| Protein Name | Leiomodin-3Leiomodin - Fetal Form |
| Database Links | |
| Cellular Localisation | CytoplasmMyofibrilSarcomereM LineA BandCytoskeletonHighly Expressed In Nonstriated Areas Of Developing MyotubesWhere It Shows A Granular Cytoplasmic PatternIn SarcomeresHighly Expressed In The M Band Region AndAt Lower LevelsAlong Actin Thin FilamentsNot Detected In Z-DisksMay Be Located NearBut Not AtActin Thin Filament Pointed End |
| Alternative Antibody Names | Anti-Leiomodin-3 antibodyAnti-Leiomodin - Fetal Form antibodyAnti-LMOD3 antibody |
Information sourced from Uniprot.org
