| Host: |
Rabbit |
| Applications: |
WB/IHC |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-LIM and cysteine-rich domains protein 1 (270-320 aa) is suitable for use in Western Blot and Immunohistochemistry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000IHC-P 1:50-300 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
LMCD1 |
| Gene ID: |
29995 |
| Uniprot ID: |
LMCD1_HUMAN |
| Immunogen Region: |
270-320 aa |
| Specificity: |
This antibody detects endogenous levels of LMCD1 at Human/Mouse |
| Immunogen: |
Synthesized peptide derived from the human LMCD1 at the amino acid range 270-320 |
| Function | Transcriptional cofactor that restricts GATA6 function by inhibiting DNA-binding, resulting in repression of GATA6 transcriptional activation of downstream target genes. Represses GATA6-mediated trans activation of lung- and cardiac tissue-specific promoters. Inhibits DNA-binding by GATA4 and GATA1 to the cTNC promoter. Plays a critical role in the development of cardiac hypertrophy via activation of calcineurin/nuclear factor of activated T-cells signaling pathway. |
| Protein Name | Lim And Cysteine-Rich Domains Protein 1Dyxin |
| Database Links | Reactome: R-HSA-5683826 |
| Cellular Localisation | CytoplasmNucleusMay Shuttle Between The Cytoplasm And The Nucleus |
| Alternative Antibody Names | Anti-Lim And Cysteine-Rich Domains Protein 1 antibodyAnti-Dyxin antibodyAnti-LMCD1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
