| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:200-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | LMAN2 |
| Gene ID: | 10960 |
| Uniprot ID: | LMAN2_HUMAN |
| Immunogen Region: | 190-320 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 190-320 of human LMAN2 (NP_006807.1). |
| Immunogen Sequence: | HSKDGRWTELAGCTADFRNR DHDTFLAVRYSRGRLTVMTD LEDKNEWKNCIDITGVRLPT GYYFGASAGTGDLSDNHDII SMKLFQLMVEHTPDEESIDW TKIEPSVNFLKSPKDNVDDP TGNFRSGPLTG |
| Tissue Specificity | Ubiquitous. |
| Function | Plays a role as an intracellular lectin in the early secretory pathway. Interacts with N-acetyl-D-galactosamine and high-mannose type glycans and may also bind to O-linked glycans. Involved in the transport and sorting of glycoproteins carrying high mannose-type glycans. |
| Protein Name | Vesicular Integral-Membrane Protein Vip36Glycoprotein Gp36bLectin Mannose-Binding 2Vesicular Integral-Membrane Protein 36Vip36 |
| Database Links | Reactome: R-HSA-204005Reactome: R-HSA-5694530 |
| Cellular Localisation | Endoplasmic Reticulum-Golgi Intermediate Compartment MembraneSingle-Pass Type I Membrane ProteinGolgi Apparatus MembraneSingle-Pass Membrane ProteinEndoplasmic Reticulum Membrane |
| Alternative Antibody Names | Anti-Vesicular Integral-Membrane Protein Vip36 antibodyAnti-Glycoprotein Gp36b antibodyAnti-Lectin Mannose-Binding 2 antibodyAnti-Vesicular Integral-Membrane Protein 36 antibodyAnti-Vip36 antibodyAnti-LMAN2 antibodyAnti-C5orf8 antibody |
Information sourced from Uniprot.org