| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Protein ERGIC-53 is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | LMAN1 |
| Gene ID: | 3998 |
| Uniprot ID: | LMAN1_HUMAN |
| Specificity: | This antibody detects endogenous levels of ERGIC-53 at Human, Mouse, Rat |
| Immunogen: | Synthesized peptide derived from human ERGIC-53 |
| Post Translational Modifications | The N-terminal may be partly blocked. |
| Function | Mannose-specific lectin. May recognize sugar residues of glycoproteins, glycolipids, or glycosylphosphatidyl inositol anchors and may be involved in the sorting or recycling of proteins, lipids, or both. The LMAN1-MCFD2 complex forms a specific cargo receptor for the ER-to-Golgi transport of selected proteins. |
| Protein Name | Protein Ergic-53Er-Golgi Intermediate Compartment 53 Kda ProteinGp58Intracellular Mannose-Specific Lectin Mr60Lectin Mannose-Binding 1 |
| Database Links | Reactome: R-HSA-204005Reactome: R-HSA-5694530Reactome: R-HSA-8980692Reactome: R-HSA-9013106Reactome: R-HSA-9013404Reactome: R-HSA-9013405Reactome: R-HSA-9013408Reactome: R-HSA-9013423Reactome: R-HSA-948021 |
| Cellular Localisation | Endoplasmic Reticulum-Golgi Intermediate Compartment MembraneSingle-Pass Type I Membrane ProteinGolgi Apparatus MembraneSingle-Pass Membrane ProteinEndoplasmic Reticulum Membrane |
| Alternative Antibody Names | Anti-Protein Ergic-53 antibodyAnti-Er-Golgi Intermediate Compartment 53 Kda Protein antibodyAnti-Gp58 antibodyAnti-Intracellular Mannose-Specific Lectin Mr60 antibodyAnti-Lectin Mannose-Binding 1 antibodyAnti-LMAN1 antibodyAnti-ERGIC53 antibodyAnti-F5F8D antibody |
Information sourced from Uniprot.org
