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Anti-LMAN1 antibody (1-100) [S2MR] (STJ11102202)

Immunohistochemistry analysis of paraffin-embedded human placenta using LMAN1 Rabbit monoclonal antibody (STJ11102202) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM Tris/EDTA buffer pH 9. 0 before commencing with immunohistochemistry staining protocol.
Immunohistochemistry analysis of paraffin-embedded human appendix using LMAN1 Rabbit monoclonal antibody (STJ11102202) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM Tris/EDTA buffer pH 9. 0 before commencing with immunohistochemistry staining protocol.
Immunohistochemistry analysis of paraffin-embedded rat brain using LMAN1 Rabbit monoclonal antibody (STJ11102202) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM Tris/EDTA buffer pH 9. 0 before commencing with immunohistochemistry staining protocol.
Western blot analysis of extracts of various cell lines, using LMAN1 Rabbit monoclonal antibody (STJ11102202) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.

Anti-LMAN1 antibody (1-100) [S2MR] (STJ11102202)

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STJ11102202

£146.50 - £639.50

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General Information
Product Properties
Target Information
Additional Info
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Host:	Rabbit
Applications:	WB/IHC
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit monoclonal antibody anti-LMAN1 (1-100) is suitable for use in Western Blot and Immunohistochemistry research applications.

Clonality:	Monoclonal
Clone ID:	S2MR
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:2000 IHC-P 1:50-1:200
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	LMAN1
Gene ID:	3998
Uniprot ID:	LMAN1_HUMAN
Immunogen Region:	1-100
Immunogen:	A synthetic peptide corresponding to a sequence within amino acids 1-100 of human LMAN1 (P49257).
Immunogen Sequence:	MAGSRQRGLRARVRPLFCAL LLSLGRFVRGDGVGGDPAVA LPHRRFEYKYSFKGPHLVQS DGTVPFWAHAGNAIPSSDQI RVAPSLKSQRGSVWTKTKAA

Tissue Specificity	Ubiquitous.
Post Translational Modifications	The N-terminal may be partly blocked.
Function	Mannose-specific lectin. May recognize sugar residues of glycoproteins, glycolipids, or glycosylphosphatidyl inositol anchors and may be involved in the sorting or recycling of proteins, lipids, or both. The LMAN1-MCFD2 complex forms a specific cargo receptor for the ER-to-Golgi transport of selected proteins.
Protein Name	Protein Ergic-53 Er-Golgi Intermediate Compartment 53 Kda Protein Gp58 Intracellular Mannose-Specific Lectin Mr60 Lectin Mannose-Binding 1
Database Links	Reactome: R-HSA-204005 Reactome: R-HSA-5694530 Reactome: R-HSA-8980692 Reactome: R-HSA-9013106 Reactome: R-HSA-9013404 Reactome: R-HSA-9013405 Reactome: R-HSA-9013408 Reactome: R-HSA-9013423 Reactome: R-HSA-948021
Cellular Localisation	Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Single-Pass Type I Membrane Protein Golgi Apparatus Membrane Single-Pass Membrane Protein Endoplasmic Reticulum Membrane
Alternative Antibody Names	Anti-Protein Ergic-53 antibody Anti-Er-Golgi Intermediate Compartment 53 Kda Protein antibody Anti-Gp58 antibody Anti-Intracellular Mannose-Specific Lectin Mr60 antibody Anti-Lectin Mannose-Binding 1 antibody Anti-LMAN1 antibody Anti-ERGIC53 antibody Anti-F5F8D antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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