Anti-LIPT1 antibody (N-Term) (STJA0010366)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human N-ternal LIPT
General Information
| Short Description | Rabbit polyclonal anti-Lipoyltransferase 1, mitochondrial (N-Term) for use in IHC and WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000IHC 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | LIPT1 |
| Gene ID | 51601 |
| Uniprot ID | LIPT_HUMAN |
| Immunogen | Synthesized peptide derived from human N-ternal LIPT |
| Immunogen Region | N-Term |
| Specificity | This antibody detects endogenous levels of LIPT at Human, Mouse |
Additional Info
| Function | Lipoyl amidotransferase that catalyzes the transfer of lipoyl moieties from lipoyl-protein H of the glycine cleavage system (lipoyl-GCSH) to E2 subunits of the pyruvate dehydrogenase complex (PDCE2). Unable to catalyze the transfer of octanoyl from octanoyl-GCSH to PDCE2. In vitro, it is also able to catalyze the transfer of the lipoyl group from lipoyl-AMP to the specific lysine residue of lipoyl domains of lipoate-dependent enzymes but this reaction may not be physiologically relevant (Probable). |
| Protein Name | Lipoyl Amidotransferase Lipt1 - MitochondrialLipoate Biosynthesis ProteinLipoate-Protein LigaseLipoyl LigaseLipoyltransferase 1 |
| Database Links | Reactome: R-HSA-9857492 |
| Cellular Localisation | Mitochondrion |
| Alternative Antibody Names | Anti-Lipoyl Amidotransferase Lipt1 - Mitochondrial antibodyAnti-Lipoate Biosynthesis Protein antibodyAnti-Lipoate-Protein Ligase antibodyAnti-Lipoyl Ligase antibodyAnti-Lipoyltransferase 1 antibodyAnti-LIPT1 antibody |
Information sourced from Uniprot.org