| Host: | Rabbit |
| Applications: | IHC/WB |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Lipoyltransferase 1, mitochondrial (N-Term) is suitable for use in Immunohistochemistry and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000IHC 1:50-200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | LIPT1 |
| Gene ID: | 51601 |
| Uniprot ID: | LIPT_HUMAN |
| Immunogen Region: | N-Term |
| Specificity: | This antibody detects endogenous levels of LIPT at Human, Mouse |
| Immunogen: | Synthesized peptide derived from human N-ternal LIPT |
| Function | Lipoyl amidotransferase that catalyzes the transfer of lipoyl moieties from lipoyl-protein H of the glycine cleavage system (lipoyl-GCSH) to E2 subunits of the pyruvate dehydrogenase complex (PDCE2). Unable to catalyze the transfer of octanoyl from octanoyl-GCSH to PDCE2. In vitro, it is also able to catalyze the transfer of the lipoyl group from lipoyl-AMP to the specific lysine residue of lipoyl domains of lipoate-dependent enzymes but this reaction may not be physiologically relevant (Probable). |
| Protein Name | Lipoyl Amidotransferase Lipt1 - MitochondrialLipoate Biosynthesis ProteinLipoate-Protein LigaseLipoyl LigaseLipoyltransferase 1 |
| Database Links | Reactome: R-HSA-9857492 |
| Cellular Localisation | Mitochondrion |
| Alternative Antibody Names | Anti-Lipoyl Amidotransferase Lipt1 - Mitochondrial antibodyAnti-Lipoate Biosynthesis Protein antibodyAnti-Lipoate-Protein Ligase antibodyAnti-Lipoyl Ligase antibodyAnti-Lipoyltransferase 1 antibodyAnti-LIPT1 antibody |
Information sourced from Uniprot.org