| Short Description : | Rabbit polyclonal LIPG (251-500) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | LIPG |
| Gene ID: | 9388 |
| Uniprot ID: | LIPG_HUMAN |
| Immunogen Region: | 251-500 |
| Immunogen Sequence: | GCGLNDVLGSIAYGTITEVV KCEHERAVHLFVDSLVNQDK PSFAFQCTDSNRFKKGICLS CRKNRCNSIGYNAKKMRNKR NSKMYLKTRAGMPFRVYHYQ MKIHVFSYKNMGEIEPTFYV TLYGTNADSQTLPLEIVERI EQNATNTFLVYTEEDLGDLL KIQLTWEGASQSWYNLWKEF RSYLSQPRNPGRELNIRRIR VKSGETQRKLTFCTEDPENT SISPGRELWFRKCRDGWRM |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 251-500 of human LIPG (NP_006024.1). |
| Tissue Specificity | High level of expression in the liver, placenta, lung, thyroid, kidney, testis and in the corpus luteum of the ovary. Expressed also in coronary artery endothelial cells, umbilical vein endothelial cells and in hepatocytes and osteosarcoma cell lines. Not detected in heart, brain and muscle. |
| Function | Exerts both phospholipase and triglyceride lipase activities. More active as a phospholipase than a triglyceride lipase. Hydrolyzes triglycerides, both with short-chain fatty acyl groups (tributyrin) and long-chain fatty acyl groups (triolein) with similar levels of activity toward both types of substrates. Hydrolyzes high density lipoproteins (HDL) more efficiently than other lipoproteins. |
| Protein Name | Endothelial LipaseEndothelial Cell-Derived LipaseEdlElPhospholipase A1 |
| Database Links | Reactome: R-HSA-8964058 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Endothelial Lipase antibodyAnti-Endothelial Cell-Derived Lipase antibodyAnti-Edl antibodyAnti-El antibodyAnti-Phospholipase A1 antibodyAnti-LIPG antibodyAnti-UNQ387 antibodyAnti-PRO719 antibody |
Information sourced from Uniprot.org
