Post Translational Modifications | N-glycosylated. Contains predominantly high-mannose glycans. |
Function | Functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors. Is also an important negative regulator of oligodentrocyte differentiation and axonal myelination. Acts in conjunction with RTN4 and RTN4R in regulating neuronal precursor cell motility during cortical development. |
Protein Name | Leucine-Rich Repeat And Immunoglobulin-Like Domain-Containing Nogo Receptor-Interacting Protein 1Leucine-Rich Repeat And Immunoglobulin Domain-Containing Protein 1Leucine-Rich Repeat Neuronal Protein 1Leucine-Rich Repeat Neuronal Protein 6a |
Database Links | Reactome: R-HSA-193634 |
Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
Alternative Antibody Names | Anti-Leucine-Rich Repeat And Immunoglobulin-Like Domain-Containing Nogo Receptor-Interacting Protein 1 antibodyAnti-Leucine-Rich Repeat And Immunoglobulin Domain-Containing Protein 1 antibodyAnti-Leucine-Rich Repeat Neuronal Protein 1 antibodyAnti-Leucine-Rich Repeat Neuronal Protein 6a antibodyAnti-LINGO1 antibodyAnti-LERN1 antibodyAnti-LRRN6A antibodyAnti-UNQ201 antibodyAnti-PRO227 antibody |
Information sourced from Uniprot.org