![Anti-LIMS1 antibody [5G7] (STJ98322)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/124x110/products/120470/230403/STJ98322_4_ELISA__49329.1602854718.jpg?c=1 "Anti-LIMS1 antibody [5G7] (STJ98322)")
![Anti-LIMS1 antibody [5G7] (STJ98322)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/1280x1280/products/120470/230403/STJ98322_4_ELISA__49329.1602854718.jpg?c=1 "Anti-LIMS1 antibody [5G7] (STJ98322)")
| Short Description : | Mouse monoclonal anti-LIM and senescent cell antigen-like-containing domain protein 1 for use in WB, IF, FC and ELISA in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IF/FC/ELISA |
| Host: | Mouse |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | 5G7 |
| Isotype: | IgG1 |
| Conjugation: | Unconjugated |
| Purification: | Affinity purification |
| Dilution Range: | WB 1:500-1:2000IF 1:200-1:1000FC 1:200-1:400ELISA 1:10000 |
| Formulation: | Liquid in PBS containing 0.03% Sodium Azide, 0.5% BSA, 50% Glycerol. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | LIMS1 |
| Gene ID: | 3987 |
| Uniprot ID: | LIMS1_HUMAN |
| Immunogen: | Purified recombinant fragment of human Pinch-1 expressed in E. Coli. |
| Specificity: | Pinch-1 Monoclonal Antibody detects endogenous levels of Pinch-1 protein. |
| Function | Within the IPP (ILK-PINCH-PARVIN) complex, binds to F-actin, promoting F-actin bundling, a process required to generate force for actin cytoskeleton reorganization and subsequent dynamic cell adhesion events such as cell spreading and migration. |
| Protein Name | Lim And Senescent Cell Antigen-Like-Containing Domain Protein 1Particularly Interesting New Cys-His Protein 1Pinch-1Renal Carcinoma Antigen Ny-Ren-48 |
| Database Links | Reactome: R-HSA-446353Reactome: R-HSA-446388 |
| Cellular Localisation | Cell JunctionFocal AdhesionCell MembranePeripheral Membrane ProteinCytoplasmic Side |
| Alternative Antibody Names | Anti-Lim And Senescent Cell Antigen-Like-Containing Domain Protein 1 antibodyAnti-Particularly Interesting New Cys-His Protein 1 antibodyAnti-Pinch-1 antibodyAnti-Renal Carcinoma Antigen Ny-Ren-48 antibodyAnti-LIMS1 antibodyAnti-PINCH antibodyAnti-PINCH1 antibody |
Information sourced from Uniprot.org
