Anti-LIMS1 antibody (1-325) (STJ115853)

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STJ115853
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Host: Rabbit
Applications: WB/IF/ICC/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
IF/ICC:1:50-1:200
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: LIMS1
Gene ID: 3987
Uniprot ID: LIMS1_HUMAN
Immunogen Region: 1-325
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 1-325 of human LIMS1 (NP_001180417.1).
Immunogen Sequence: MANALASATCERCKGGFAPA EKIVNSNGELYHEQCFVCAQ CFQQFPEGLFYEFEGRKYCE HDFQMLFAPCCHQCGEFIIG RVIKAMNNSWHPECFRCDLC QEVLADIGFVKNAGRHLCRP CHNREKARGLGKYICQKCHA IIDEQPLIFKNDPYHPDHFN CANCGKELTADARELKGELY CLPCHDKMGVPICGACRRPI EGRVVNAMGKQWHVEHFVCA KCEKPFLGHRHYERKGLAY
Tissue Specificity Expressed in most tissues except in the brain.
Function Within the IPP (ILK-PINCH-PARVIN) complex, binds to F-actin, promoting F-actin bundling, a process required to generate force for actin cytoskeleton reorganization and subsequent dynamic cell adhesion events such as cell spreading and migration.
Protein Name Lim And Senescent Cell Antigen-Like-Containing Domain Protein 1
Particularly Interesting New Cys-His Protein 1
Pinch-1
Renal Carcinoma Antigen Ny-Ren-48
Database Links Reactome: R-HSA-446353
Reactome: R-HSA-446388
Cellular Localisation Cell Junction
Focal Adhesion
Cell Membrane
Peripheral Membrane Protein
Cytoplasmic Side
Alternative Antibody Names Anti-Lim And Senescent Cell Antigen-Like-Containing Domain Protein 1 antibody
Anti-Particularly Interesting New Cys-His Protein 1 antibody
Anti-Pinch-1 antibody
Anti-Renal Carcinoma Antigen Ny-Ren-48 antibody
Anti-LIMS1 antibody
Anti-PINCH antibody
Anti-PINCH1 antibody

Information sourced from Uniprot.org