Host: | Rabbit |
Applications: | WB/ELISA |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Clonality : | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
Purification: | Affinity purification |
Concentration: | Lot specific |
Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | LIM2 |
Gene ID: | 3982 |
Uniprot ID: | LMIP_HUMAN |
Immunogen Region: | 25-110 |
Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 25-110 of human LIM2 (NP_085915.2). |
Immunogen Sequence: | TDHWMQYRLSGSFAHQGLWR YCLGNKCYLQTDSIGEPPGQ GPGRAWGKSRADLGAQGHLY SRWRTLRLKEGKGATQAYWN ATRAFM |
Tissue Specificity | Eye lens specific. |
Function | Present in the thicker 16-17 nm junctions of mammalian lens fiber cells, where it may contribute to cell junctional organization. Acts as a receptor for calmodulin. May play an important role in both lens development and cataractogenesis. |
Protein Name | Lens Fiber Membrane Intrinsic ProteinMp18Mp19Mp20 |
Cellular Localisation | MembraneMulti-Pass Membrane Protein |
Alternative Antibody Names | Anti-Lens Fiber Membrane Intrinsic Protein antibodyAnti-Mp18 antibodyAnti-Mp19 antibodyAnti-Mp20 antibodyAnti-LIM2 antibody |
Information sourced from Uniprot.org