| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | LIFR |
| Gene ID: | 3977 |
| Uniprot ID: | LIFR_HUMAN |
| Immunogen Region: | 500-700 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 500-700 of human LIFR (NP_002301.1). |
| Immunogen Sequence: | NPYTLYTFRIRCSTETFWKW SKWSNKKQHLTTEASPSKGP DTWREWSSDGKNLIIYWKPL PINEANGKILSYNVSCSSDE ETQSLSEIPDPQHKAEIRLD KNDYIISVVAKNSVGSSPPS KIASMEIPNDDLKIEQVVGM GKGILLTWHYDPNMTCDYVI KWCNSSRSEPCLMDWRKVPS NSTETVIESDEFRPGIRYNF F |
| Function | Signal-transducing molecule. May have a common pathway with IL6ST. The soluble form inhibits the biological activity of LIF by blocking its binding to receptors on target cells. |
| Protein Name | Leukemia Inhibitory Factor ReceptorLif ReceptorLif-RCd Antigen Cd118 |
| Database Links | Reactome: R-HSA-6788467Reactome: R-HSA-8939247 |
| Cellular Localisation | Isoform 1: Cell MembraneSingle-Pass Type I Membrane ProteinIsoform 2: Secreted |
| Alternative Antibody Names | Anti-Leukemia Inhibitory Factor Receptor antibodyAnti-Lif Receptor antibodyAnti-Lif-R antibodyAnti-Cd Antigen Cd118 antibodyAnti-LIFR antibody |
Information sourced from Uniprot.org
![Western blot analysis of lysates from wild type (WT) and SUGP2 knockout (KO) HeLa cells, using [KO Validated] SUGP2 Rabbit polyclonal antibody (STJ11100764) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/600x533/products/89701/358185/STJ11100764_1__27808.1713122498.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and SUGP2 knockout (KO) HeLa cells, using [KO Validated] SUGP2 Rabbit polyclonal antibody (STJ11100764) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.")
