| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Rat/Deer |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Galectin-1 (10-90 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000 ELISA 1:40000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | LGALS1 |
| Gene ID: | 3956 |
| Uniprot ID: | LEG1_HUMAN |
| Immunogen Region: | 10-90 aa |
| Specificity: | Galectin-1 Polyclonal Antibody detects endogenous levels of Galectin-1 protein. |
| Immunogen: | Synthesized peptide derived from Galectin-1 at the amino acid range 10-90 |
| Function | Lectin that binds beta-galactoside and a wide array of complex carbohydrates. Plays a role in regulating apoptosis, cell proliferation and cell differentiation. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase. Strong inducer of T-cell apoptosis. Plays a negative role in Th17 cell differentiation via activation of the receptor CD69. |
| Protein Name | Galectin-1 Gal-1 14 Kda Laminin-Binding Protein Hlbp14 14 Kda Lectin Beta-Galactoside-Binding Lectin L-14-I Galaptin Hbl Hpl Lactose-Binding Lectin 1 Lectin Galactoside-Binding Soluble 1 Putative Mapk-Activating Protein Pm12 S-Lac Lectin 1 |
| Database Links | Reactome: R-HSA-381426 Reactome: R-HSA-8957275 |
| Cellular Localisation | Secreted Extracellular Space Extracellular Matrix Cytoplasm Can Be Secreted The Secretion Is Dependent On Protein Unfolding And Facilitated By The Cargo Receptor Tmed10 It Results In Protein Translocation From The Cytoplasm Into The Ergic (Endoplasmic Reticulum-Golgi Intermediate Compartment) Followed By Vesicle Entry And Secretion |
| Alternative Antibody Names | Anti-Galectin-1 antibody Anti-Gal-1 antibody Anti-14 Kda Laminin-Binding Protein antibody Anti-Hlbp14 antibody Anti-14 Kda Lectin antibody Anti-Beta-Galactoside-Binding Lectin L-14-I antibody Anti-Galaptin antibody Anti-Hbl antibody Anti-Hpl antibody Anti-Lactose-Binding Lectin 1 antibody Anti-Lectin Galactoside-Binding Soluble 1 antibody Anti-Putative Mapk-Activating Protein Pm12 antibody Anti-S-Lac Lectin 1 antibody Anti-LGALS1 antibody |
Information sourced from Uniprot.org
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KL
04/11/2019
Kristian L.
Anti-Galectin-1 antibody (STJ93201)
Application Used: Immunofluorescence Tissue: tongue and liver Dilution: 1:100 Secondary Antibody: Alexa Fluor Plus 594 Secondary Antibody Dilution: 1:500 Negative Control: serial section with no I Ab Tissue Processing: Froxen tissues fixed with cold acetone 100% Blocking: PBS 1x BSA 5% Triton X 0.05% Primary Probing: PBS 1x BSA 5%
