• Western blot analysis of lysates from HUVEC and MCF-7 cells, using LFNG Antibody. The lane on the right is blocked with the synthesized peptide.
  • Western blot analysis of 3T3 cells using Lunatic Fringe Polyclonal Antibody diluted at 1：1000

Anti-LFNG antibody (121-170 aa) (STJ93970)

SKU:
STJ93970

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Beta-1, 3-N-acetylglucosaminyltransferase lunatic fringe (121-170 aa) is suitable for use in Western Blot and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
ELISA 1:10000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: LFNG
Gene ID: 3955
Uniprot ID: LFNG_HUMAN
Immunogen Region: 121-170 aa
Specificity: Lunatic Fringe Polyclonal Antibody detects endogenous levels of Lunatic Fringe protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human LFNG at the amino acid range 121-170
Function Glycosyltransferase that initiates the elongation of O-linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules. Modulates NOTCH1 activity by modifying O-fucose residues at specific EGF-like domains resulting in inhibition of NOTCH1 activation by JAG1 and enhancement of NOTCH1 activation by DLL1 via an increase in its binding to DLL1. Decreases the binding of JAG1 to NOTCH2 but not that of DLL1. Essential mediator of somite segmentation and patterning.
Protein Name Beta-1 -3-N-Acetylglucosaminyltransferase Lunatic Fringe
O-Fucosylpeptide 3-Beta-N-Acetylglucosaminyltransferase
Database Links Reactome: R-HSA-1912420
Reactome: R-HSA-5083630
Reactome: R-HSA-9824272
Cellular Localisation Golgi Apparatus Membrane
Single-Pass Type Ii Membrane Protein
Alternative Antibody Names Anti-Beta-1 -3-N-Acetylglucosaminyltransferase Lunatic Fringe antibody
Anti-O-Fucosylpeptide 3-Beta-N-Acetylglucosaminyltransferase antibody
Anti-LFNG antibody

Information sourced from Uniprot.org

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