Anti-Lefty antibody (301-350 aa) (STJ97342)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the C-terminal region of human LEFTY1/LEFTY2 at the amino acid range 301-350
General Information
| Short Description | Rabbit polyclonal anti-Left-right determination factor 1 and Left-right determination factor 2 (301-350 aa) for use in WB and IHC in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000IHC-P 1:50-300 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | LEFTY2LEFTY1 |
| Gene ID | 704410637 |
| Uniprot ID | LFTY2_HUMANLFTY1_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the C-terminal region of human LEFTY1/LEFTY2 at the amino acid range 301-350 |
| Immunogen Region | 301-350 aa |
| Specificity | Lefty Polyclonal Antibody detects endogenous levels of Lefty protein. |
Additional Info
| Function | Required for left-right axis determination as a regulator of LEFTY2 and NODAL. |
| Protein Name | Left-Right Determination Factor 1Left-Right Determination Factor BProtein Lefty-1Protein Lefty-B |
| Database Links | Reactome: R-HSA-1181150Reactome: R-HSA-1433617 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Left-Right Determination Factor 1 antibodyAnti-Left-Right Determination Factor B antibodyAnti-Protein Lefty-1 antibodyAnti-Protein Lefty-B antibodyAnti-LEFTY1 antibodyAnti-LEFTB antibodyAnti-LEFTYB antibodyAnti-UNQ278 antibodyAnti-PRO317 antibody |
Information sourced from Uniprot.org