Host: | Rabbit |
Applications: | WB/IF/ICC/ELISA |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Clonality : | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
Purification: | Affinity purification |
Concentration: | Lot specific |
Dilution Range: | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | LDHB |
Gene ID: | 3945 |
Uniprot ID: | LDHB_HUMAN |
Immunogen Region: | 2-334 |
Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 2-334 of human LDHB (NP_002291.1). |
Immunogen Sequence: | ATLKEKLIAPVAEEEATVPN NKITVVGVGQVGMACAISIL GKSLADELALVDVLEDKLKG EMMDLQHGSLFLQTPKIVAD KDYSVTANSKIVVVTAGVRQ QEGESRLNLVQRNVNVFKFI IPQIVKYSPDCIIIVVSNPV DILTYVTWKLSGLPKHRVIG SGCNLDSARFRYLMAEKLGI HPSSCHGWILGEHGDSSVAV WSGVNVAGVSLQELNPEMGT DNDSENWKEVHKMVVESAY |
Tissue Specificity | Predominantly expressed in aerobic tissues such as cardiac muscle. |
Function | Interconverts simultaneously and stereospecifically pyruvate and lactate with concomitant interconversion of NADH and NAD(+). |
Protein Name | L-Lactate Dehydrogenase B ChainLdh-BLdh Heart SubunitLdh-HRenal Carcinoma Antigen Ny-Ren-46 |
Database Links | Reactome: R-HSA-70268 |
Cellular Localisation | CytoplasmMitochondrion Inner MembranePeripheral Membrane Protein |
Alternative Antibody Names | Anti-L-Lactate Dehydrogenase B Chain antibodyAnti-Ldh-B antibodyAnti-Ldh Heart Subunit antibodyAnti-Ldh-H antibodyAnti-Renal Carcinoma Antigen Ny-Ren-46 antibodyAnti-LDHB antibody |
Information sourced from Uniprot.org