| Host: | Rabbit |
| Applications: | WB/IHC-P/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | LDB3 |
| Gene ID: | 11155 |
| Uniprot ID: | LDB3_HUMAN |
| Immunogen Region: | 1-283 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-283 of human LDB3 (NP_001073585.1). |
| Immunogen Sequence: | MSYSVTLTGPGPWGFRLQGG KDFNMPLTISRITPGSKAAQ SQLSQGDLVVAIDGVNTDTM THLEAQNKIKSASYNLSLTL QKSKRPIPISTTAPPVQTPL PVIPHQKVVVNSPANADYQE RFNPSALKDSALSTHKPIEV KGLGGKATIIHAQYNTPISM YSQDAIMDAIAGQAQAQGSD FSGSLPIKDLAVDSASPVYQ AVIKSQNKPEDEADEWARRS SNLQSRSFRILAQMTGTEF |
| Tissue Specificity | Expressed primarily in skeletal muscle and to a lesser extent in heart. Also detected in brain and placenta. |
| Function | May function as an adapter in striated muscle to couple protein kinase C-mediated signaling via its LIM domains to the cytoskeleton. |
| Protein Name | Lim Domain-Binding Protein 3Protein CypherZ-Band Alternatively Spliced Pdz-Motif Protein |
| Cellular Localisation | CytoplasmPerinuclear RegionCell ProjectionPseudopodiumCytoskeletonMyofibrilSarcomereZ LineLocalized To The Cytoplasm Around Nuclei And Pseudopodia Of Undifferentiated Cells And Detected Throughout The Myotubes Of Differentiated CellsColocalizes With Actn2 At The Z-Lines |
| Alternative Antibody Names | Anti-Lim Domain-Binding Protein 3 antibodyAnti-Protein Cypher antibodyAnti-Z-Band Alternatively Spliced Pdz-Motif Protein antibodyAnti-LDB3 antibodyAnti-KIAA0613 antibodyAnti-ZASP antibody |
Information sourced from Uniprot.org